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MK-677 (Ibutamoren)

MK-677, also known as Ibutamoren or MK-0677, is a small, orally active non-peptide growth hormone secretagogue. Despite often being grouped with peptides, MK-677 is technically a small molecule (not a chain of amino acids) that mimics ghrelin and binds to the GHS-R1a receptor in the pituitary and hypothalamus. It is supplied as 25mg oral tablets for laboratory research.

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Product Specifications

  • Format: 25mg x 60 tablets
  • Class: Non-peptide GHS
  • Receptor: GHS-R1a (ghrelin)
  • Documentation available
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Research use only. Not for human or animal use.

Research Summary

  • MK-677 was originally developed for research on growth hormone deficiency and frailty in elderly populations.
  • Studies report sustained 24-hour GH and IGF-1 elevation in research subjects without suppressing endogenous GH production.
  • Unlike injectable peptides, MK-677 is orally bioavailable, making it convenient for laboratory protocols.
  • It is not FDA approved for any therapeutic indication and remains classified as a research compound.

Frequently Asked Questions

Important Disclaimer

This page is for educational and informational purposes only. This product is a research chemical sold for laboratory use only. Not intended for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider. These statements have not been evaluated by the FDA.